Title
Synthetic Brainbows.
Abstract
Brainbow is a genetic engineering technique that randomly colorizes cells. Biological samples processed with this technique and imaged with confocal microscopy have distinctive colors for individual cells. Complex cellular structures can then be easily visualized. However, the complexity of the Brainbow technique limits its applications. In practice, most confocal microscopy scans use different florescence staining with typically at most three distinct cellular structures. These structures are often packed and obscure each other in rendered images making analysis difficult. In this paper, we leverage a process known as GPU framebuffer feedback loops to synthesize Brainbow-like images. In addition, we incorporate ID shuffing and Monte-Carlo sampling into our technique, so that it can be applied to single-channel confocal microscopy data. The synthesized Brainbow images are presented to domain experts with positive feedback. A user survey demonstrates that our synthetic Brainbow technique improves visualizations of volume data with complex structures for biologists.
Year
DOI
Venue
2013
10.1111/cgf.12134
Comput. Graph. Forum
Keywords
DocType
Volume
synthesized brainbow image,complex cellular structure,confocal microscopy,complex structure,gpu framebuffer feedback loop,genetic engineering technique,confocal microscopy data,synthetic brainbows,confocal microscopy scan,brainbow technique,synthetic brainbow technique
Journal
32
Issue
ISSN
Citations 
3prt4
0167-7055
1
PageRank 
References 
Authors
0.36
13
3
Name
Order
Citations
PageRank
Y Wan1274.28
H Otsuna210.36
C Hansen330644.56