Title
Modeling airway probability.
Abstract
We present a probability model for lung airways in computed tomography (CT) images. Lung airways are tubular structures that display specific features, such as low intensity and proximity to vessels and bronchial walls. From these features, the posterior probability for the airway feature space was computed using a Bayesian model based on 20 CT images from subjects with different degrees of Chronic Obstructive Pulmonary Disease (COPD). The likelihood probability was modeled using both a Gaussian distribution and a nonparametric kernel density estimation method. After exhaustive feature selection, good specificity and sensitivity were achieved in a cross-validation study for both the Gaussian (0.83, 0.87) and the nonparametric method (0.79, 0.89). The model generalizes well when trained using images from a late stage COPD group. This probability model may facilitate airway extraction and quantitative assessment of lung diseases, which is useful in many clinical and research settings.
Year
DOI
Venue
2013
10.1109/ISBI.2013.6556491
ISBI
Keywords
Field
DocType
biomedical research,kernel,atmospheric modeling,ct,estimation theory,gaussian distribution,bioinformatics,image segmentation,feature extraction,computed tomography,computational modeling,bayesian model
Feature vector,Bayesian inference,Pattern recognition,Feature selection,Computer science,Posterior probability,Nonparametric statistics,Feature extraction,Artificial intelligence,Estimation theory,Kernel density estimation
Conference
ISSN
ISBN
Citations 
1945-7928
978-1-4673-6456-0
0
PageRank 
References 
Authors
0.34
4
7