Abstract | ||
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DNA machines consisting of consecutive hairpins, which we have previously described, have various potential applications in DNA computation. In the present study, a 288-base DNA machine containing four consecutive hairpins was successfully constructed by ligation and PCR. PAGE and fluorescence spectroscopy experiments verified that all four hairpins were successfully opened by four opener oligomers, and that hairpin opening was dependent on the proper openers added in the correct order. Quantitative analysis of the final results by fluorescence spectroscopy indicated that all four hairpins were open in about 1/4 to 1/3 of the DNA machines. |
Year | DOI | Venue |
---|---|---|
2008 | 10.1007/s11047-007-9035-y | Natural Computing |
Keywords | Field | DocType |
DNA computing,DNA nanotechnology,Molecular computing,Molecular memory,Molecular machine | Molecular machine,DNA machine,Discrete mathematics,DNA nanotechnology,Ligation,Molecular memory,Fluorescence spectroscopy,DNA,Computational biology,Bioinformatics,Mathematics,DNA computing | Journal |
Volume | Issue | Citations |
7 | 2 | 2 |
PageRank | References | Authors |
0.39 | 6 | 5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Atsushi Kameda | 1 | 62 | 9.23 |
Masahito Yamamoto | 2 | 2 | 0.39 |
Azuma Ohuchi | 3 | 386 | 68.99 |
Satsuki Yaegashi | 4 | 36 | 6.10 |
Masami Hagiya | 5 | 649 | 102.85 |