Title
The Chebi Reference Database And Ontology For Biologically Relevant Chemistry: Enhancements For 2013
Abstract
ChEBI (http://www.ebi.ac.uk/chebi) is a database and ontology of chemical entities of biological interest. Over the past few years, ChEBI has continued to grow steadily in content, and has added several new features. In addition to incorporating all user-requested compounds, our annotation efforts have emphasized immunology, natural products and metabolites in many species. All database entries are now 'is_a' classified within the ontology, meaning that all of the chemicals are available to semantic reasoning tools that harness the classification hierarchy. We have completely aligned the ontology with the Open Biomedical Ontologies (OBO) Foundry-recommended upper level Basic Formal Ontology. Furthermore, we have aligned our chemical classification with the classification of chemical-involving processes in the Gene Ontology (GO), and as a result of this effort, the majority of chemical-involving processes in GO are now defined in terms of the ChEBI entities that participate in them. This effort necessitated incorporating many additional biologically relevant compounds. We have incorporated additional data types including reference citations, and the species and component for metabolites. Finally, our website and web services have had several enhancements, most notably the provision of a dynamic new interactive graph-based ontology visualization.
Year
DOI
Venue
2013
10.1093/nar/gks1146
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
computer graphics,internet
Ontology,Biology,Chemistry,Ontology (information science),Ontology-based data integration,Process ontology,Information retrieval,Open Biomedical Ontologies,Basic Formal Ontology,Bioinformatics,Suggested Upper Merged Ontology,Genetics,Web service
Journal
Volume
Issue
ISSN
41
D1
0305-1048
Citations 
PageRank 
References 
104
6.16
21
Authors
11
Search Limit
100104
Name
Order
Citations
PageRank
Janna Hastings171462.06
Paula de Matos249243.42
Adriano Dekker328621.61
Marcus Ennis451539.59
Bhavana Harsha51589.44
Namrata Kale61558.45
Venkatesh Muthukrishnan71609.63
Gareth Owen819014.25
Steve Turner929923.43
Mark Williams1025823.62
Christoph Steinbeck11109294.06