Title
Nonthermal irreversible electroporation: fundamentals, applications, and challenges.
Abstract
Tissue ablation is an essential procedure for the treatment of many diseases. In the last decade, a nonthermal tissue ablation using intensive pulsed electric fields, called nonthermal irreversible electroporation (NTIRE), has rapidly emerged. The exact mechanisms responsible for cell death by NTIRE, however, are currently unknown. Nevertheless, the technique's remarkable ability to ablate tissue in the proximity of larger blood vessels, to preserve tissue architecture, short procedure duration, and shortened postoperative recovery period rapidly moved NTIRE from bench to bed side. This work provides an overview on the development of NTIRE, its current state-of-the-art, challenges, and future needs.
Year
DOI
Venue
2013
10.1109/TBME.2013.2238672
IEEE Trans. Biomed. Engineering
Keywords
Field
DocType
bioelectric phenomena,blood vessels,cellular biophysics,diseases,electrophoresis,surgery,blood vessels,cell death,disease treatment,intensive pulsed electric fields,nonthermal irreversible electroporation,nonthermal tissue ablation,short procedure duration,shortened post-operative recovery,tissue architecture,Irreversible electroporation,minimally invasive surgery,nonthermal ablation,pulsed electric fields
Biomedical engineering,Cellular biophysics,Computer science,Ablation,Procedure Duration,Irreversible electroporation
Journal
Volume
Issue
ISSN
60
3
1558-2531
Citations 
PageRank 
References 
0
0.34
5
Authors
2
Name
Order
Citations
PageRank
Alexander Golberg121.46
Martin L Yarmush2315.26