Title
A Non-Linear Registration Method For Dce-Mri And Dce-Ct Comparison In Bladder Tumors
Abstract
The objective of this work is to examine the feasibility of a method to register dynamic contrast enhanced computed X-ray tomography (DCE-CT) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) datasets in order to make possible the comparison of parametric maps generated from tracer kinetic modeling. First, the CT and MR dynamic sets were matched temporally using a cross-correlation maximization approach. The registration was then performed through an affine transformation followed by a non-linear registration using free-form deformations (FFDs) based on B-splines. This was determined from the CT-MR pair that maximized Normalized Mutual Information (NMI). Then the 'extended Kety' model was fitted to both CT and MR and K-trans, v(e) and v(p) parameters were obtained. The method was applied to 5 patients with bladder tumors. After registration, the overlap matching between CT and MR volume of interest (VOI) was on average 91%.
Year
DOI
Venue
2008
10.1109/ISBI.2008.4541191
2008 IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO, VOLS 1-4
Keywords
Field
DocType
registration, inter-modal, DCE-MRI, DCE-CT, tracer kinetic modeling
Affine transformation,Computer vision,Medical imaging,Computer science,Tomography,Parametric statistics,Mutual information,Artificial intelligence,Dynamic contrast-enhanced MRI,Image registration,Magnetic resonance imaging
Conference
ISSN
Citations 
PageRank 
1945-7928
0
0.34
References 
Authors
1
15