Paper Info
Title
FoldUnfold: web server for the prediction of disordered regions in protein chain
Abstract
Summary: Identification of disordered regions in polypeptide chains is very important because such regions are essential for protein function. A new parameter, namely mean packing density of residues has been introduced to detect disordered regions in a protein sequence. We have demonstrated that regions with weak expected packing density would be responsible for the appearance of disordered regions. Our method (FoldUnfold) has been tested on datasets of globular proteins (559 proteins) and long disordered protein segments (129 proteins) and showed improved performance over some other widely used methods, such as DISOPRED, PONDR VL3H, IUPred and GlobPlot. Availability: The FoldUnfold server is available for users at http://skuld.protres.ru/~mlobanov/ogu/ogu.cgi. There is a link to our server through the web site of DisProt (http://www.disprot.org/predictors.php). Contact: ogalzit@vega.protres.ru
Year
DOI
Venue
2006
10.1093/bioinformatics/btl504
Bioinformatics
Field
DocType
Volume
Protein sequencing,Globular protein,Computer science,Sphere packing,Protein function,Bioinformatics,Web server
Journal
22
Issue
ISSN
Citations 
23
1367-4803
22
PageRank 
References 
Authors
2.30
5
3
Name
Order
Citations
PageRank
Oxana V. Galzitskaya112520.15
Sergiy O. Garbuzynskiy29512.37
Michail Yu. Lobanov37910.18