Name
Title | ||
|---|---|---|
A novel non-overlapping bi-clustering algorithm for network generation using living cell array data. |
Abstract | ||
|---|---|---|
The living cell array quantifies the contribution of activated transcription factors upon the expression levels of their target genes. The direct manipulation of the regulatory mechanisms offers enormous possibilities for deciphering the machinery that activates and controls gene expression. We propose a novel bi-clustering algorithm for generating non-overlapping clusters of reporter genes and conditions and demonstrate how this information can be interpreted in order to assist in the construction of transcription factor interaction networks. |
Year | DOI | Venue |
|---|---|---|
2007 | 10.1093/bioinformatics/btm335 | Bioinformatics |
Keywords | Field | DocType |
expression level,network generation,regulatory mechanism,transcription factor interaction network,non-overlapping cluster,gene expression,direct manipulation,living cell array,bi-clustering algorithm,activated transcription factor,living cell array data,enormous possibility,reporter gene,biological assay,activating transcription factor,cluster analysis,gene expression profiling,interaction network,transcription factor,signal transduction,transcription factors | Reporter gene,Computer science,Response element,Bioinformatics,Cluster analysis,Gene regulatory network,GAL4/UAS system,Gene expression profiling,Transcription factor,Cis-regulatory module | Journal |
Volume | Issue | ISSN |
23 | 17 | 1367-4811 |
Citations | PageRank | References |
8 | 0.54 | 9 |
Authors | ||
5 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| E Yang | 1 | 18 | 2.40 |
| P T Foteinou | 2 | 8 | 0.54 |
| K R King | 3 | 8 | 0.54 |
| M L Yarmush | 4 | 10 | 1.26 |
| I P Androulakis | 5 | 10 | 1.26 |