Title
Ensemble learning for robust prediction of microRNA-mRNA interactions
Abstract
Different microRNA target prediction tools produce different results. Motivated by this fact, here we present an ensemble-learning approach that combines the outcomes from multiple tools to reduce prediction error. We test this approach with a dataset derived from a public database containing human microRNAs and microRNA-mRNA pairs. According to our experimental result, using the proposed method tends to be significantly better than using individual prediction tools in terms of increasing the area under curve (AUC) defined on a receiver operating characteristic curve.
Year
DOI
Venue
2014
10.1109/BIGCOMP.2014.6741403
BigComp
Keywords
Field
DocType
ensemble-learning approach,area under curve,robust microrna-mrna interaction prediction,learning (artificial intelligence),human micrornas,receiver operating characteristic curve,prediction error reduction,microrna-mrna pairs,auc,bioinformatics,rna,microrna target prediction tools,public database,learning artificial intelligence
Data mining,Mean squared prediction error,Receiver operating characteristic,Computer science,Artificial intelligence,Ensemble learning,Machine learning
Conference
ISSN
Citations 
PageRank 
2375-933X
0
0.34
References 
Authors
8
4
Name
Order
Citations
PageRank
Seunghak Yu100.34
Juho Kim263268.72
Hyeyoung Min3295.34
Sungroh Yoon456678.80