Title
A two-class approach to the detection of physiological deterioration in patient vital signs, with clinical label refinement.
Abstract
Hospital patient outcomes can be improved by the early identification of physiological deterioration. Automatic methods of detecting patient deterioration in vital-sign data typically attempt to identify deviations from assumed normal physiological conditions, which is a one-class approach to classification. This paper investigates the use of a two-class approach, in which abnormal physiology is modelled explicitly. The success of such a method relies on the accuracy of data labels provided by clinical experts, which may be incomplete (due to large dataset size) or imprecise (due to clinical labels covering intervals, rather than each data point within those intervals). We propose a novel method of refining clinical labels such that the two-class classification approach may be adopted for identifying patient deterioration. We demonstrate the effectiveness of the proposed methods using a large dataset acquired in a 24-bed hospital step-down unit.
Year
DOI
Venue
2012
10.1109/TITB.2012.2212202
IEEE Transactions on Information Technology in Biomedicine
Keywords
Field
DocType
probability density function,support vector machines,biomedical engineering
Data science,Data mining,Novelty detection,Computer science,Support vector machine,Vital signs,Artificial intelligence,Machine learning
Journal
Volume
Issue
ISSN
16
6
1558-0032
Citations 
PageRank 
References 
2
0.45
2
Authors
4
Name
Order
Citations
PageRank
S Khalid122.14
D Clifton222224.26
L Clifton320212.53
Lionel Tarassenko4643118.09