Title
Genome Surveyor 2.0: cis-regulatory analysis in Drosophila.
Abstract
Genome Surveyor 2.0 is a web-based tool for discovery and analysis of cis-regulatory elements in Drosophila, built on top of the GBrowse genome browser for convenient visualization. Genome Surveyor was developed as a tool for predicting transcription factor (TF) binding targets and cis-regulatory modules (CRMs/enhancers), based on motifs representing experimentally determined DNA binding specificities. Since its first publication, we have added substantial new functionality (e.g. phylogenetic averaging of motif scores from multiple species, and a novel CRM discovery technique), increased the number of supported motifs about 4-fold (from similar to 100 to similar to 400), added provisions for evolutionary comparison across many more Drosophila species (from 2 to 12), and improved the user-interface. The server is free and open to all users, and there is no login requirement. Address: http://veda.cs.uiuc.edu/gs.
Year
DOI
Venue
2011
10.1093/nar/gkr291
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
binding sites,transcription factors
Genome,REDfly,Phylogenetic tree,Biology,Genome browser,DNA,Genetics,Enhancer,Drosophila melanogaster,Transcription factor
Journal
Volume
Issue
ISSN
39
SUPnan
0305-1048
Citations 
PageRank 
References 
2
0.40
7
Authors
3
Name
Order
Citations
PageRank
Majid Kazemian1464.45
Michael H Brodsky2161.53
Saurabh Sinha352948.96