Abstract | ||
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Genome Surveyor 2.0 is a web-based tool for discovery and analysis of cis-regulatory elements in Drosophila, built on top of the GBrowse genome browser for convenient visualization. Genome Surveyor was developed as a tool for predicting transcription factor (TF) binding targets and cis-regulatory modules (CRMs/enhancers), based on motifs representing experimentally determined DNA binding specificities. Since its first publication, we have added substantial new functionality (e.g. phylogenetic averaging of motif scores from multiple species, and a novel CRM discovery technique), increased the number of supported motifs about 4-fold (from similar to 100 to similar to 400), added provisions for evolutionary comparison across many more Drosophila species (from 2 to 12), and improved the user-interface. The server is free and open to all users, and there is no login requirement. Address: http://veda.cs.uiuc.edu/gs. |
Year | DOI | Venue |
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2011 | 10.1093/nar/gkr291 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
binding sites,transcription factors | Genome,REDfly,Phylogenetic tree,Biology,Genome browser,DNA,Genetics,Enhancer,Drosophila melanogaster,Transcription factor | Journal |
Volume | Issue | ISSN |
39 | SUPnan | 0305-1048 |
Citations | PageRank | References |
2 | 0.40 | 7 |
Authors | ||
3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Majid Kazemian | 1 | 46 | 4.45 |
Michael H Brodsky | 2 | 16 | 1.53 |
Saurabh Sinha | 3 | 529 | 48.96 |