Title
Biological workflow with BlastQuest
Abstract
Besides domain-specific biological problems, biologists are confronted with many computational problems. The large amount of varying, heterogeneous, and semi-structured biological data, the increasing complexity of biological applications, methods, and tools afflicted with uncertainty and missing knowledge, as well as the lacking interoperability of available tools necessitate integrative measures to enable biology workflow. In this paper we address these problems in the context of the processing and evaluation of BLAST query results. We present a new tool, called BlastQuest, which relies on database technology and provides sophisticated interactive and Web-enabled query, analysis, and visualization facilities for genomics data. The interface with the Gene Ontology and the KEGG pathway databases decisively foster the biological workflow. Finally, based on our experience with BlastQuest, we briefly sketch a new concept, called Genomies Algebra, for solving genomic data management problems from a broader perspective.
Year
DOI
Venue
2005
10.1016/j.datak.2004.06.014
Data Knowl. Eng.
Keywords
Field
DocType
blast,web-enabled query,domain-specific biological problem,genomics data,blast query result,unifying database,new concept,genomics algebra,semi-structured biological data,genomic data management problem,biological workflow,gene ontology,biological application,biology workflow,kegg pathway database,biological data,data management
Biological data,Data mining,Computational problem,Visualization,Interoperability,Computer science,KEGG,Data management,Workflow,Database,Sketch
Journal
Volume
Issue
ISSN
53
1
0169-023X
Citations 
PageRank 
References 
1
0.40
8
Authors
5
Name
Order
Citations
PageRank
william g farmerie a1675.23
Joachim Hammer216817.35
li liu a3534.29
anuj sahni a410.40
Markus Schneider563665.46