Title
Brain plasticity in recovery from stroke: an MEG assessment.
Abstract
The aim of this paper was to deepen understanding about the role played by brain plasticity in obtaining clinical recovery. Eighteen patients, who had recovered partially or totally from dysfunctions due to a monohemispheric infarction within the middle cerebral artery territory, underwent magnetoencephalographic (MEG) recordings of rolandic areas cerebral activity both in rest state (spectral power properties) and in response to the electrical stimulation of the contralateral median nerve (M20 and M30 cortical sources). MEG evaluation was performed in acute (T0: mean 5 days from ischemic attach) and post-acute phase (T1: median 6 months). At T1, all the inter-hemispheric asymmetries were reduced for both spontaneous and evoked activity parameters with respect to T0. In post-acute phase, lower cortical excitability, higher delta and theta power and lower spectral entropy were associated to a worse clinical state. An unusual recruitment–as revealed by an excessive inter-hemispheric asymmetry of M20 cortical source position–correlated with higher level of clinical amelioration in the patients who showed a partial recovery.
Year
DOI
Venue
2006
10.1016/j.neuroimage.2006.05.004
NeuroImage
Keywords
Field
DocType
resting state,acute phase,brain plasticity
Developmental psychology,Median nerve,Infarction,Middle cerebral artery,Psychology,Stroke,Neural activity,Total recovery,Neuroplasticity,Stimulation
Journal
Volume
Issue
ISSN
32
3
1053-8119
Citations 
PageRank 
References 
7
1.01
3
Authors
9