Name
Abstract | ||
|---|---|---|
This paper introduces a model for simulating regulatory networks that is capable of reproducing spatial and temporal expression patterns in developmental processes. The model is a generalization of the standard connectionist model used for modelling genetic interactions, where the terms for the regulation of gene products and the diffusion term have been separated. This model can be coupled with biomechanical models of cell aggregates and used to study the formation of spatial and temporal expression patterns of gene products during development in cellular systems. |
Year | DOI | Venue |
|---|---|---|
2003 | 10.1007/3-540-44864-0_71 | International Conference on Computational Science |
Keywords | Field | DocType |
cellular system,genetic interaction,standard connectionist model,developmental regulatory network,diffusion term,cell aggregate,developmental process,biomechanical model,temporal expression pattern,reproducing spatial,gene product,genetics | Computer science,Artificial intelligence,Biological cell,Machine learning,Connectionism | Conference |
Volume | ISSN | ISBN |
2660 | 0302-9743 | 3-540-40197-0 |
Citations | PageRank | References |
0 | 0.34 | 1 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Tommy Krul | 1 | 0 | 0.34 |
| Jaap A. Kaandorp | 2 | 110 | 19.07 |
| Joke G Blom | 3 | 161 | 23.43 |