Title
Mechanisms in biomedical ontology.
Abstract
The concept of a mechanism has become a standard proposal for explanations in biology. It has been claimed that mechanistic explanations are appropriate for systems biology, because they occupy a middle ground between strict reductionism and holism. Because of their importance in the field a formal ontological description of mechanisms is desirable. The standard philosophical accounts of mechanisms are often ambiguous and lack the clarity that can be provided by a formal-ontological framework. The goal of this paper is to clarify some of these ambiguities and suggest such a framework for mechanisms. Taking some hints from an "ontology of devices" I suggest as a general approach for this task the introduction of functional kinds and functional parts by which the particular relations between a mechanism and its components can be captured.
Year
DOI
Venue
2012
10.1186/2041-1480-3-S2-S9
J. Biomedical Semantics
Keywords
Field
DocType
bioinformatics,biomedical research
Data science,Ontology,Holism,Data mining,CLARITY,Computer science,Systems biology,Reductionism,Mechanism (philosophy)
Journal
Volume
Issue
ISSN
3 Suppl 2
S-2
2041-1480
Citations 
PageRank 
References 
2
0.38
4
Authors
1
Name
Order
Citations
PageRank
Johannes Röhl121.73