Paper Info
Title
Ectopic Foci Study on the Crest Terminalis in 3D Computer Model of Human Atrial.
Abstract
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. Epidemiological studies show that AF tends to persist over time, creating electrophysiological and anatomical changes called remodeled atrial. It has been shown that these changes result in variations in conduction velocity (CV) in the atrial tissue. The changes caused by electrical remodeling in a model of action potential (AP) of atrial myocytes have been incorpotated in this study, coupled with an anatomically realistic three-dimensional model of human dilated atrium. Simulations of the spread of AP in terms of anatomical and electrical remodeling and remodeling of gap junctions were measured vulnerable windows of reentry generation on the crest terminalis of the atrium. The results obtained indicate that vulnerable window in the remodeling of gap junctions shined 38 ms with respect to the model dilated, which shows the impact of structural remodeling Several types of permanent reentry of figures in form of eight and in form of rotor, favored by the underlying anatomy of the atrium were obtained.
Year
DOI
Venue
2012
10.1007/978-3-642-28839-5_18
6TH INTERNATIONAL CONFERENCE ON PRACTICAL APPLICATIONS OF COMPUTATIONAL BIOLOGY & BIOINFORMATICS
Keywords
Field
DocType
Atrial fibrillation,electrical remodeling,action potential,cresta terminalis,reentry,3D model
Atrial fibrillation,Crest,Myocyte,Neuroscience,Atrium (architecture),Gap junction,Nerve conduction velocity,Internal medicine,Cardiology,Reentry,Medicine,Electrophysiology
Conference
Volume
ISSN
Citations 
154
1867-5662
0
PageRank 
References 
Authors
0.34
2
4
Name
Order
Citations
PageRank
Carlos A. Ruiz-Villa100.34
Andrés P. Castaño220.77
Andrés Castillo3273.41
Elvio Heidenreich420.70