Name
Title | ||
|---|---|---|
Effects of geometry and architecture on re-entrant scroll wave dynamics in human virtual ventricular tissues |
Abstract | ||
|---|---|---|
We examine the effects of cardiac geometry and architecture on re-entrant scroll wave dynamics by quantifying the scroll wave filament in two biophysically-detailed heterogeneous models of the human left ventricular free wall - a simple cuboid model and a wedge model constructed using DT-MRI data. For any given geometry, changing the architecture results in changes to the filament meander pattern, increases in filament length, changes to the filament curvature and local filament twist, and increases in the maximum twist along a single filament. Changes to the geometry also affect scroll wave dynamics, mainly due to the size of the tissue. We conclude that such differences in reentrant scroll wave dynamics should be taken into account when interpreting results from simulations that use simple cardiac geometries and architectures. |
Year | DOI | Venue |
|---|---|---|
2007 | 10.1007/978-3-540-72907-5_21 | FIMH |
Keywords | Field | DocType |
cardiac geometry,single filament,filament length,reentrant scroll wave dynamic,filament curvature,scroll wave filament,re-entrant scroll wave dynamic,filament meander pattern,local filament twist,human virtual ventricular tissue,scroll wave dynamic,diffusion tensor,magnetic resonance image | Twist,Scroll,Curvature,Protein filament,Wedge (mechanical device),Cuboid,Geometry,Meander,Physics,Reentrancy | Conference |
Volume | ISSN | Citations |
4466 | 0302-9743 | 1 |
PageRank | References | Authors |
0.48 | 1 | 3 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Alan P. Benson | 1 | 4 | 5.14 |
| Michael E. Ries | 2 | 1 | 0.82 |
| Arun V. Holden | 3 | 52 | 20.71 |