Paper Info
Title
rSNP_Guide, a database system for analysis of transcription factor binding to target sequences: application to SNPs and site-directed mutations
Abstract
rSNP_Guide is a novel curated database system for analysis of transcription factor (TF) binding to target sequences in regulatory gene regions altered by mutations. It accumulates experimental data on naturally occurring site variants in regulatory gene regions and site-directed mutations. This database system also contains the web tools for SNP analysis, i.e,, active applet applying weight matrices to predict the regulatory site candidates altered by a mutation. The current version of the rSNP_Guide is supplemented by six sub-databases: (i) rSNP_DB, on DNA-protein interaction caused by mutation; (ii) SYSTEM, on experimental systems; (iii) rSNP_BIB, on citations to original publications; (iv) SAMPLES, on experimentally identified sequences of known regulatory sites; (v) MATRIX, on weight matrices of known TF sites; (vi) rSNP_Report, on characteristic examples of successful rSNP_Tools implementation. These databases are useful for the analysis of natural SNPs and site-directed mutations. The databases are available through the Web, http://wwwmgs.bionet.nsc.ru/mgs/ systems/rsnp/.
Year
DOI
Venue
2001
10.1093/nar/29.1.312
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Binding site,Biology,SNP array,DNA,Single-nucleotide polymorphism,Regulator gene,Regulatory site,Genetics,Molecular biology,Transcription factor,Database,Mutation
Journal
29
Issue
ISSN
Citations 
1
0305-1048
8
PageRank 
References 
Authors
1.32
9
10
Name
Order
Citations
PageRank
Julia V. Ponomarenko125724.02
Tatyana I. Merkulova211412.70
Gennady V. Vasiliev3143.03
Zoya B. Levashova481.32
Galina Orlova5387.54
Lavryushev S V6213.76
Oleg N. Fokin7183.19
Mikhail P Ponomarenko813127.97
Anatoly S. Frolov910015.56
Akinori Sarai1044546.27