Name
Title | ||
|---|---|---|
Quantifying Effects of Class I Anti-arrhythmic Drugs in Human Virtual Cardiac Tissues |
Abstract | ||
|---|---|---|
Ventricular tachycardia and fibrillation are dangerous cardiac arrhythmias. Anti-arrhythmic drugs such as lidocaine (a class I drug) reinstate normal sinus rhythm, but they have pro-arrhythmic side effects and their mechanisms of action are poorly understood. We used computational models of human ventricular tissues to elucidate and quantify these mechanisms. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1007/978-3-540-70521-5_23 | ISBMS |
Keywords | Field | DocType |
dangerous cardiac arrhythmias,anti-arrhythmic drug,ventricular tachycardia,class i anti-arrhythmic drugs,quantifying effects,pro-arrhythmic side effect,human virtual cardiac tissues,human ventricular tissue,normal sinus rhythm,computational model,computer model,side effect | Fibrillation,Internal medicine,Cardiology,Anesthesia,Normal Sinus Rhythm,Ventricular tachycardia,Lidocaine,Drug,Medicine | Conference |
Volume | ISSN | Citations |
5104 | 0302-9743 | 0 |
PageRank | References | Authors |
0.34 | 1 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Alan P. Benson | 1 | 4 | 5.14 |
| Jennifer A. Lawrenson | 2 | 0 | 0.34 |
| Stephen H. Gilbert | 3 | 15 | 4.55 |
| Arun V. Holden | 4 | 52 | 20.71 |