Title
Finding short DNA motifs using permuted Markov models.
Abstract
Many short DNA motifs, such as transcription factor binding sites (TFBS) and splice sites, exhibit strong local as well as nonlocal dependence. We introduce permuted variable length Markov models (PVLMM) which could capture the potentially important dependencies among positions and apply them to the problem of detecting splice and TFB sites. They have been satisfactory from the viewpoint of prediction performance and also give ready biological interpretations of the sequence dependence observed. The issue of model selection is also studied.
Year
DOI
Venue
2005
10.1089/cmb.2005.12.894
Journal of Computational Biology
Keywords
DocType
Volume
model selection,markov model
Journal
12
Issue
ISSN
ISBN
6
1066-5277
1-58113-755-9
Citations 
PageRank 
References 
29
1.37
16
Authors
3
Name
Order
Citations
PageRank
Xiaoyue Zhao1384.15
Haiyan Huang2518.76
Terence P. Speed3973122.30