Title
The change in cerebrovascular reactivity between 3 T and 7 T measured using graded hypercapnia.
Abstract
Mapping cerebrovascular reactivity (CVR) to hypercapnia is important both clinically and for improved understanding of the haemodynamic properties of the BOLD effect. In this work, BOLD/R2⁎ CVR was investigated by using a device which provided small, repeatable and stable steps in PETCO2, whilst maintaining a steady PETO2 level. Significant CVR was observed in both grey and white matter at both 3 and 7 T, whilst an approximately linear relationship found between R2⁎ CVR and field strength has implications for BOLD models and calibration. Grey matter R2⁎ CVR was 0.066±0.004 s−1 mm Hg−1 at 3 T and 0.141±0.008 s−1 mm Hg−1 at 7 T. White matter R2⁎ CVR was 0.021±0.003 s−1 mm Hg−1 at 3 T and 0.040±0.007 s−1 mm Hg−1 at 7 T.
Year
DOI
Venue
2010
10.1016/j.neuroimage.2009.12.113
NeuroImage
Field
DocType
Volume
Hemodynamics,Grey matter,White matter,Internal medicine,Cerebrovascular Circulation,Cardiology,Psychology,Cognitive psychology,Hypercapnia,Pathology
Journal
51
Issue
ISSN
Citations 
1
1053-8119
6
PageRank 
References 
Authors
0.58
7
5
Name
Order
Citations
PageRank
ian d driver1484.54
Nicholas Blockley2998.41
joseph a fisher3161.15
Susan Francis41046.68
Penny Gowland5564.51