Title | ||
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The change in cerebrovascular reactivity between 3 T and 7 T measured using graded hypercapnia. |
Abstract | ||
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Mapping cerebrovascular reactivity (CVR) to hypercapnia is important both clinically and for improved understanding of the haemodynamic properties of the BOLD effect. In this work, BOLD/R2⁎ CVR was investigated by using a device which provided small, repeatable and stable steps in PETCO2, whilst maintaining a steady PETO2 level. Significant CVR was observed in both grey and white matter at both 3 and 7 T, whilst an approximately linear relationship found between R2⁎ CVR and field strength has implications for BOLD models and calibration. Grey matter R2⁎ CVR was 0.066±0.004 s−1 mm Hg−1 at 3 T and 0.141±0.008 s−1 mm Hg−1 at 7 T. White matter R2⁎ CVR was 0.021±0.003 s−1 mm Hg−1 at 3 T and 0.040±0.007 s−1 mm Hg−1 at 7 T. |
Year | DOI | Venue |
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2010 | 10.1016/j.neuroimage.2009.12.113 | NeuroImage |
Field | DocType | Volume |
Hemodynamics,Grey matter,White matter,Internal medicine,Cerebrovascular Circulation,Cardiology,Psychology,Cognitive psychology,Hypercapnia,Pathology | Journal | 51 |
Issue | ISSN | Citations |
1 | 1053-8119 | 6 |
PageRank | References | Authors |
0.58 | 7 | 5 |
Name | Order | Citations | PageRank |
---|---|---|---|
ian d driver | 1 | 48 | 4.54 |
Nicholas Blockley | 2 | 99 | 8.41 |
joseph a fisher | 3 | 16 | 1.15 |
Susan Francis | 4 | 104 | 6.68 |
Penny Gowland | 5 | 56 | 4.51 |