Name
Title | ||
|---|---|---|
An Exact Algorithm For Determining Protein Backbone Structure From NH Residual Dipolar Couplings |
Abstract | ||
|---|---|---|
We have developed a novel algorithm for protein backbone structure determination using global orientational restraints on internuclear bond vectors derived from residual dipolar couplings (RDCs) measured in solution NMR. The algorithm is a depth-first search (DFS) strategy that is built upon two low-degree polynomial equations for computing the backbone (phi, psi) angles, exactly and in constant time, from two bond vectors in consecutive peptide planes. |
Year | DOI | Venue |
|---|---|---|
2003 | 10.1109/CSB.2003.1227422 | CSB |
Keywords | Field | DocType |
nh residual dipolar couplings,exact algorithm,protein backbone structure,residual dipolar coupling,depth first search,genetic algorithms,proteins | Residual,Molecular physics,Crystallography,Coupling,Exact algorithm,Polynomial,Chemistry,Residual dipolar coupling,Artificial intelligence,Peptide bond,Dipole,Machine learning | Conference |
ISBN | Citations | PageRank |
0-7695-2000-6 | 1 | 0.46 |
References | Authors | |
0 | 4 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Lincong Wang | 1 | 52 | 6.23 |
| Ramgopal R. Mettu | 2 | 177 | 22.23 |
| Ryan Lilien | 3 | 54 | 4.25 |
| Bruce Donald | 4 | 1859 | 335.89 |