Title
Fabrication and analysis of hollow microneedles and polymeric piezoelectric valveless micropump for transdermal drug-delivery system.
Abstract
This study presents the fabrication and analysis of silicon hollow microneedles and polymeric piezoelectric valveless micropump for microelectromechanical (MEMS)-based transdermal drug-delivery (TDD) system. The proposed TDD system consists of integrated control electronics and MEMS devices such as micropump, microneedles, blood pressure sensor and fluid flow sensor. Microneedles and micropump are the most essential and critical components of the proposed TDD system. Mechanical strength of microneedles has been investigated in structural analysis. Inductively coupled plasma technology has been used to fabricate high aspect ratio silicon hollow microneedles. The numerical analysis of micropump has been done by building three-dimensional electro-fluid-solid model. The experimental performance of fabricated polymeric piezoelectric valveless micropump with different pump chamber diameters has been characterised in terms of actuator deflection and flow rate at different operational parameters.
Year
DOI
Venue
2012
10.1049/iet-com.2011.0177
IET Communications
Keywords
Field
DocType
bioMEMS,biomedical electronics,blood pressure measurement,drug delivery systems,flow sensors,microfabrication,micropumps,needles,piezoelectric actuators,plasma materials processing,pressure sensors,3D electro-fluid-solid model,MEMS based TDD system,MEMS based transdermal drug delivery system,MEMS devices,actuator deflection,blood pressure sensor,flow rate,fluid flow sensor,high aspect ratio silicon hollow microneedles,inductively coupled plasma technology,integrated control electronics,microelectromechanical system,microneedle mechanical strength,micropump numerical analysis,polymeric piezoelectric valveless micropump,structural analysis
Microelectromechanical systems,Transdermal,Real-time computing,Micropump,Optoelectronics,Fabrication,Silicon,Volumetric flow rate,Mathematics,Actuator,Piezoelectricity
Journal
Volume
Issue
ISSN
6
18
1751-8628
Citations 
PageRank 
References 
0
0.34
0
Authors
4
Name
Order
Citations
PageRank
Muhammad Waseem Ashraf143.16
Shahzadi Tayyaba243.84
Asim Nisar300.68
Nitin Afzulpurkar48511.98