Title
Ideal observer comparison between tomographic and projection x-ray images of the breast
Abstract
The image data from 348 breast CT studies performed on patient volunteers in a Phase II clinical trial were used in a pre-whitened matched filter (PWMF) model observer study This computer-based investigation simulated the addition of spherical lesions of various diameters to the breast data sets, and a series of images with different slice thicknesses ranging from 0.3 mm to 44 mm were created by voxel averaging The PWMF was tailored to each slice thickness, and signal known exactly receiver operating characteristic analysis was performed A total of 1000 lesions and “non-lesions” were simulated for each diameter on each breast data set Receiver operating characteristic (ROC) curve analysis was performed, and sensitivity at 95% specificity was computed Thin slice imaging as with breast CT demonstrated significantly better sensitivity than thick slice images as with mammography, with improvements in sensitivity ranging from 5% to 50%.
Year
DOI
Venue
2010
10.1007/978-3-642-13666-5_80
Digital Mammography / IWDM
Keywords
Field
DocType
projection x-ray image,breast data,breast ct,image data,breast ct study,different slice,breast data set,thin slice imaging,better sensitivity,thick slice image,slice thickness,ideal observer comparison,receiver operating characteristic curve,receiver operator characteristic,roc curve,observational study,matched filter
Voxel,Nuclear medicine,Mammography,Computer vision,Data set,X-ray,Receiver operating characteristic,Ranging,Artificial intelligence,Matched filter,Observer (quantum physics),Mathematics
Conference
Volume
ISSN
ISBN
6136
0302-9743
3-642-13665-6
Citations 
PageRank 
References 
0
0.34
1
Authors
3
Name
Order
Citations
PageRank
John M. Boone14310.07
Nathan J. Packard242.02
Craig K. Abbey35417.61