Title
Neuroimaging in aphasia treatment research: Standards for establishing the effects of treatment.
Abstract
The goal of this paper is to discuss experimental design options available for establishing the effects of treatment in studies that aim to examine the neural mechanisms associated with treatment-induced language recovery in aphasia, using functional magnetic resonance imaging (fMRI). We present both group and single-subject experimental or case-series design options for doing this and address advantages and disadvantages of each. We also discuss general components of and requirements for treatment research studies, including operational definitions of variables, criteria for defining behavioral change and treatment efficacy, and reliability of measurement. Important considerations that are unique to neuroimaging-based treatment research are addressed, pertaining to the relation between the selected treatment approach and anticipated changes in language processes/functions and how such changes are hypothesized to map onto the brain.
Year
DOI
Venue
2013
10.1016/j.neuroimage.2012.10.011
NeuroImage
Keywords
Field
DocType
Aphasia,Language recovery,fMRI,Treatment efficacy
Brain mapping,Research design,Developmental psychology,Functional magnetic resonance imaging,Cognitive psychology,Functional imaging,Aphasia,Psychology,Neuroimaging,Aphasia Treatment,Operational definition
Journal
Volume
Issue
ISSN
76
1.0
1053-8119
Citations 
PageRank 
References 
0
0.34
8
Authors
8