Title
BioCichlid: central dogma-based 3D visualization system of time-course microarray data on a hierarchical biological network.
Abstract
BioCichlid is a 3D visualization system of time-course microarray data on molecular networks, aiming at interpretation of gene expression data by transcriptional relationships based on the central dogma with physical and genetic interactions. BioCichlid visualizes both physical (protein) and genetic (regulatory) network layers, and provides animation of time-course gene expression data on the genetic network layer. Transcriptional regulations are represented to bridge the physical network (transcription factors) and genetic network (regulated genes) layers, thus integrating promoter analysis into the pathway mapping. BioCichlid enhances the interpretation of microarray data and allows for revealing the underlying mechanisms causing differential gene expressions.
Year
DOI
Venue
2009
10.1093/bioinformatics/btp008
BIOINFORMATICS
Keywords
Field
DocType
biological network,3d visualization,microarray data
Data mining,Gene,Microarray,Expression (mathematics),Visualization,Biological network,Computer science,Gene expression,Microarray analysis techniques,Bioinformatics,Microarray databases
Journal
Volume
Issue
ISSN
25
4
1367-4803
Citations 
PageRank 
References 
1
0.35
2
Authors
4
Name
Order
Citations
PageRank
Ryosuke R Ishiwata1112.03
Masaki S Morioka210.35
Soichi Ogishima3707.08
Hiroshi Tanaka494.43