Title
A Multidimensional Flow Cytometry Data Classification
Abstract
Flow has been widely used for the diagnosis of various diseases. We proposed an automated gating approach to analyze and cluster flow data and provide researchers and physicians a 3-D way of viewing flow data. This automated approach was designed to give reproducible results, which avoid the subjective and time-consuming human manipulation. Doublets problem will be eliminated by our tool, and the result were compared with the manual gating. In addition, a 3D visualization will not only give a user-friendly representation but also avert misclassification would occur in lower dimension. We demonstrated how the 3D approach can be used to augment the K-means method in classifying the data. To validate the feasibility of our proposed automatic approach, our result is compared with the result done at the Methodist Hospital in Houston.
Year
DOI
Venue
2009
10.1109/BIBE.2009.20
BIBE
Keywords
Field
DocType
reproducible result,time-consuming human manipulation,manual gating,multidimensional flow cytometry data,biomedical measurement,classifying thedata,k-means method,multidimensional flow cytometry data classification,automated approach,proposed automatic approach,flow visualisation,cluster flowdata,automated gating approach,3d visualization,hematopoietic diseases,methodist hospital,doublets problem,haemodynamics,blood,data analysis,fluorescence,k means,flow cytometry,scattering parameters,multidimensional systems,data visualization,clustering algorithms
Data mining,Data visualization,Gating,Visualization,Computer science,Artificial intelligence,Bioinformatics,Data classification,Cluster analysis,Flow visualization,Machine learning
Conference
ISSN
ISBN
Citations 
2471-7819
978-0-7695-3656-9
0
PageRank 
References 
Authors
0.34
3
3
Name
Order
Citations
PageRank
Ming-Chih Shih1222.06
Shou-hsuan Stephen Huang217459.88
Chung-Che Jeff Chang3372.46