Title
TreeFam: a curated database of phylogenetic trees of animal gene families.
Abstract
TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as well as reliable ortholog and paralog assignments. Curated families are being added progressively, based on seed alignments and trees in a similar fashion to Pfam. Release 1.1 of TreeFam contains curated trees for 690 families 25 and automatically generated trees for another 11 646 families. These represent over 128 000 genes from nine fully sequenced animal genomes and over 45 000 other animal proteins from UniProt; similar to 40 - 85% of proteins encoded in the fully sequenced animal genomes are included in TreeFam. TreeFam is freely available at http://www.treefam.org and http://treefam.genomics.org.cn.
Year
DOI
Venue
2006
10.1093/nar/gkj118
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
paralogs,duplication,phylogenetic tree,proteins,resources,genome,genomics,genes,phylogenomics,protein families,evolution,internet,orthologs,gene family,phylogeny
Genome,TreeFam,Phylogenetic tree,Biology,UniProt,Genomics,Phylogenomics,Phylogenetics,Genetics,Gene family,Database
Journal
Volume
Issue
ISSN
34
Database issue
0305-1048
Citations 
PageRank 
References 
67
8.43
23
Authors
15
Name
Order
Citations
PageRank
Heng Li13109302.06
Avril Coghlan215816.37
Jue Ruan31108157.57
Lachlan James M Coin412916.07
Jean-Karim Hériché512815.09
Lara Osmotherly6678.43
Ruiqiang Li776591.23
Tao Liu811614.03
Zhang Zhang917228.00
Lars Bolund1016318.92
Gane Ka-Shu Wong1116217.81
Weimou Zheng12678.43
Paramvir Dehal13678.43
Jun Wang149228736.82
Richard Durbin1562031201.66