Title
Biophysical annotation and representation of CellML models
Abstract
Motivation: CellML is an implementation-independent model description language for specifying and exchanging biological processes. The focus of CellML is the representation of mathematical formulations of biological processes. The language captures the mathematical and model building constructs well, but does not lend itself to capturing the biology these models represent. Results: This article describes the development of an ontological framework for annotating CellML models with biophysical concepts. We demonstrate that, by using these ontological mappings, in combination with a set of graph reduction rules, it is possible to represent the underlying biological process described in a CellML model. Contact: sarala.dissanayake@auckland.ac.nz Supplementary information: Supplementary data are available at Bioinformatics online.
Year
DOI
Venue
2009
10.1093/bioinformatics/btp391
Bioinformatics
Field
DocType
Volume
Ontology,Data mining,CellML,Annotation,Computer science,Model building,Natural language processing,Artificial intelligence,Bioinformatics,Graph reduction
Journal
25
Issue
ISSN
Citations 
17
1367-4803
4
PageRank 
References 
Authors
0.52
6
5
Name
Order
Citations
PageRank
S. M. Wimalaratne151.14
M. D. B. Halstead251.14
C. M. Lloyd351.14
E. J. Crampin451.14
Mjolsness E D5831101.83