Name
Title | ||
|---|---|---|
Ein Beitrag zu einer Theorie lebender Zellen (A Contribution towards a Theory of Living Cells) |
Abstract | ||
|---|---|---|
The following article describes systems biology as a merger of systems theory with cell biology. The role of modelling in the description of living cells is discussed. As an example, an abstract multiple-level model of a cell is developed. It is shown that a level of elementary cellular processes, realising cell functions, and a coordination-level are sufficient to create a system that is closed with respect to efficient causation. This form of self-organisation is thereby considered as basic criterion by which living systems, such as cells and organisms, are distinguished from machines and computers. Die causal closure of the cell is possible through the definition of the cell model as a cartesian closed category. It follows the conclusion that computer simulations of differential equations may be able to reproduce cellular processes but not this aspect of causal closure. The article ends with a discussion about the role of systems theory in the life sciences. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1524/auto.2008.0707 | AT-AUTOMATISIERUNGSTECHNIK |
Keywords | Field | DocType |
systems theory,cell biology,systems biology,processes,function,self-organisation,causality | Systems biology,Control engineering,Engineering,Epistemology,Self organisation | Journal |
Volume | Issue | ISSN |
56 | 5 | 0178-2312 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
2 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Olaf Wolkenhauer | 1 | 330 | 40.25 |
| Hofmeyr J-H | 2 | 883 | 124.40 |