Title
Automated detection of obstructive sleep apnoea syndrome from oxygen saturation recordings using linear discriminant analysis
Abstract
Nocturnal polysomnography (PSG) is the gold-standard to diagnose obstructive sleep apnoea syndrome (OSAS). However, it is complex, expensive, and time-consuming. We present an automatic OSAS detection algorithm based on classification of nocturnal oxygen saturation (SaO2) recordings. The algorithm makes use of spectral and nonlinear analysis for feature extraction, principal component analysis (PCA) for preprocessing and linear discriminant analysis (LDA) for classification. We conducted a study to characterize and prospectively validate our OSAS detection algorithm. The population under study was composed of subjects suspected of suffering from OSAS. A total of 214 SaO2 signals were available. These signals were randomly divided into a training set (85 signals) and a test set (129 signals) to prospectively validate the proposed method. The OSAS detection algorithm achieved a diagnostic accuracy of 93.02% (97.00% sensitivity and 79.31% specificity) on the test set. It outperformed other alternative implementations that either use spectral and nonlinear features separately or are based on logistic regression (LR). The proposed method could be a useful tool to assist in early OSAS diagnosis, contributing to overcome the difficulties of conventional PSG.
Year
DOI
Venue
2010
10.1007/s11517-010-0646-6
Med. Biol. Engineering and Computing
Keywords
Field
DocType
Obstructive sleep apnoea syndrome, Oxygen saturation, Linear discriminant analysis, Spectral analysis, Nonlinear analysis, Pattern classification
Population,Pattern recognition,Speech recognition,Feature extraction,Preprocessor,Artificial intelligence,Linear discriminant analysis,Logistic regression,Principal component analysis,Mathematics,Polysomnography,Test set
Journal
Volume
Issue
ISSN
48
9
1741-0444
Citations 
PageRank 
References 
17
1.53
11
Authors
5
Name
Order
Citations
PageRank
J. Víctor Marcos1757.13
Roberto Hornero260367.74
Daniel Álvarez321225.22
Félix del Campo412618.12
Mateo Aboy529740.03