Title
Statistical Analysis of Textural Features for Improved Classification of Oral Histopathological Images
Abstract
The objective of this paper is to provide an improved technique, which can assist oncopathologists in correct screening of oral precancerous conditions specially oral submucous fibrosis (OSF) with significant accuracy on the basis of collagen fibres in the sub-epithelial connective tissue. The proposed scheme is composed of collagen fibres segmentation, its textural feature extraction and selection, screening perfomance enhancement under Gaussian transformation and finally classification. In this study, collagen fibres are segmented on R,G,B color channels using back-probagation neural network from 60 normal and 59 OSF histological images followed by histogram specification for reducing the stain intensity variation. Henceforth, textural features of collgen area are extracted using fractal approaches viz., differential box counting and brownian motion curve . Feature selection is done using Kullback---Leibler (KL) divergence criterion and the screening performance is evaluated based on various statistical tests to conform Gaussian nature. Here, the screening performance is enhanced under Gaussian transformation of the non-Gaussian features using hybrid distribution. Moreover, the routine screening is designed based on two statistical classifiers viz., Bayesian classification and support vector machines (SVM) to classify normal and OSF. It is observed that SVM with linear kernel function provides better classification accuracy (91.64%) as compared to Bayesian classifier. The addition of fractal features of collagen under Gaussian transformation improves Bayesian classifier's performance from 80.69% to 90.75%. Results are here studied and discussed.
Year
DOI
Venue
2012
10.1007/s10916-010-9550-8
J. Medical Systems
Keywords
Field
DocType
Oral cancer, Collagen, Texture, Statistical tests, Bayesian classifier, Support vector machine
Histogram,Naive Bayes classifier,Feature selection,Pattern recognition,Support vector machine,Feature extraction,Gaussian,Artificial intelligence,Box counting,Medicine,Kernel (statistics)
Journal
Volume
Issue
ISSN
36
2
1573-689X
Citations 
PageRank 
References 
6
0.73
9
Authors
4
Name
Order
Citations
PageRank
M. Muthu Rama Krishnan11307.14
Pratik Shah2235.31
Chandan Chakraborty353750.60
Ajoy K. Ray424717.23