Title
CAD/CAM and rapid prototyped scaffold construction for bone regenerative medicine and surgical transfer of virtual planning: A pilot study.
Abstract
We developed a model to test new bone constructs to replace spare skeletal segments originating from new generation scaffolds for bone marrow-derived mesenchymal stem cells. Using computed tomography (CT) data, scaffolds were defined using computer-aided design/computer-aided manufacturing (CAD/CAM) for rapid prototyping by three-dimensional (3D) printing. A bone defect was created in pig mandible ramus by condyle resection for CT and CAD/CAM elaboration of bone volume for cutting and scaffold restoration. The protocol produced a perfect-fitting bone substitute model for rapid prototyped hydroxyapatite (HA) scaffolds. A surgical guide system was developed to accurately reproduce virtually planned bone sectioning procedures in animal models to obtain a perfect fit during surgery.
Year
DOI
Venue
2009
10.1016/j.compmedimag.2008.10.005
Computerized Medical Imaging and Graphics
Keywords
DocType
Volume
Maxillofacial prosthesis,CAD–CAM,Scaffold,Rapid prototyping,Bone regeneration
Journal
33
Issue
ISSN
Citations 
1
0895-6111
4
PageRank 
References 
Authors
1.37
0
4
Name
Order
Citations
PageRank
L Ciocca162.82
F De Crescenzio2233.17
M Fantini341.37
R Scotti442.05