Title
Context-constrained multiple instance learning for histopathology image segmentation.
Abstract
Histopathology image segmentation plays a very important role in cancer diagnosis and therapeutic treatment. Existing supervised approaches for image segmentation require a large amount of high quality manual delineations (on pixels), which is often hard to obtain. In this paper, we propose a new algorithm along the line of weakly supervised learning; we introduce context constraints as a prior for multiple instance learning (ccMIL), which significantly reduces the ambiguity in weak supervision (a 20% gain); our method utilizes image-level labels to learn an integrated model to perform histopathology cancer image segmentation, clustering, and classification. Experimental results on colon histopathology images demonstrate the great advantages of ccMIL.
Year
DOI
Venue
2012
10.1007/978-3-642-33454-2_77
Lecture Notes in Computer Science
Field
DocType
Volume
Computer vision,Scale-space segmentation,Pattern recognition,Computer science,Local binary patterns,Supervised learning,Image segmentation,Pixel,Artificial intelligence,Cluster analysis,Ambiguity
Conference
7512
Issue
ISSN
Citations 
Pt 3
0302-9743
15
PageRank 
References 
Authors
0.65
10
5
Name
Order
Citations
PageRank
Yan Xu124316.75
Jianwen Zhang231914.74
Eric I-Chao Chang326112.68
Maode Lai41214.81
Zhuowen Tu53663215.79