Title
ViPR: an open bioinformatics database and analysis resource for virology research.
Abstract
The Virus Pathogen Database and Analysis Resource (ViPR, www.ViPRbrc.org) is an integrated repository of data and analysis tools for multiple virus families, supported by the National Institute of Allergy and Infectious Diseases (NIAID) Bioinformatics Resource Centers (BRC) program. ViPR contains information for human pathogenic viruses belonging to the Arenaviridae, Bunyaviridae, Caliciviridae, Coronaviridae, Flaviviridae, Filoviridae, Hepeviridae, Herpesviridae, Paramyxoviridae, Picornaviridae, Poxviridae, Reoviridae, Rhabdoviridae and Togaviridae families, with plans to support additional virus families in the future. ViPR captures various types of information, including sequence records, gene and protein annotations, 3D protein structures, immune epitope locations, clinical and surveillance metadata and novel data derived from comparative genomics analysis. Analytical and visualization tools for metadata-driven statistical sequence analysis, multiple sequence alignment, phylogenetic tree construction, BLAST comparison and sequence variation determination are also provided. Data filtering and analysis workflows can be combined and the results saved in personal 'Workbenches' for future use. ViPR tools and data are available without charge as a service to the virology research community to help facilitate the development of diagnostics, prophylactics and therapeutics for priority pathogens and other viruses.
Year
DOI
Venue
2012
10.1093/nar/gkr859
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Filoviridae,Biology,Genomics,Comparative genomics,Protein Annotation,Bioinformatics,Multiple sequence alignment,Genetics,Virology,Virus Pathogen Database and Analysis Resource,Virus classification,Sequence analysis
Journal
40
Issue
ISSN
Citations 
D1
0305-1048
15
PageRank 
References 
Authors
0.86
16
15
Name
Order
Citations
PageRank
Brett E. Pickett1150.86
Eva L. Sadat2150.86
Y. Zhang328839.66
Jyothi Noronha4293.65
Burke Squires5364.24
Victoria Hunt6293.65
Mengya Liu7151.20
Sanjeev Kumar82727139.04
Sam Zaremba9382.26
Zhiping Gu101329.49
Liwei Zhou11161.63
Christopher N. Larson12150.86
Jonathan Dietrich13241.24
Edward B. Klem14161.29
Richard H. Scheuermann1525823.91