Title
Cultured neurons coupled to microelectrode arrays: circuit models, simulations and experimental data.
Abstract
The purpose of this paper is to characterize the neuron-microelectrode junction, based on the equivalent electric-circuit approach. As a result, recording of action potentials can be simulated with a general-purpose circuit simulation program such as HSPICE. The response of the microelectrode was analyzed as a function of parameters such as sealing resistance and adhesion conditions. The models of the neuron and microelectrode implemented in HSPICE were first described. These models were used to simulate the behavior of the junction between a patch of neuronal membrane (described by the compartmental model) and a microelectrode.
Year
DOI
Venue
2004
10.1109/TBME.2004.826607
IEEE Trans. Biomed. Engineering
Keywords
Field
DocType
bioelectric potentials,biological techniques,biomedical electrodes,biomembrane transport,microelectrodes,neurophysiology,HSPICE,action potentials,adhesion,circuit models,compartmental model,cultured neurons,equivalent electric-circuit approach,extracellular recording,general-purpose circuit simulation program,microelectrode arrays,neuro-electronic junction,neuron-microelectrode junction,neuronal membrane,sealing resistance
Experimental data,Neurophysiology,Computer science,Electronic engineering,Circuit models,Microelectrode
Journal
Volume
Issue
ISSN
51
5
0018-9294
Citations 
PageRank 
References 
20
2.92
4
Authors
4
Name
Order
Citations
PageRank
S Martinoia115820.68
Paolo Massobrio2213.62
Marco Bove3274.90
Giuseppe Massobrio4203.26