Title | ||
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Cultured neurons coupled to microelectrode arrays: circuit models, simulations and experimental data. |
Abstract | ||
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The purpose of this paper is to characterize the neuron-microelectrode junction, based on the equivalent electric-circuit approach. As a result, recording of action potentials can be simulated with a general-purpose circuit simulation program such as HSPICE. The response of the microelectrode was analyzed as a function of parameters such as sealing resistance and adhesion conditions. The models of the neuron and microelectrode implemented in HSPICE were first described. These models were used to simulate the behavior of the junction between a patch of neuronal membrane (described by the compartmental model) and a microelectrode. |
Year | DOI | Venue |
---|---|---|
2004 | 10.1109/TBME.2004.826607 | IEEE Trans. Biomed. Engineering |
Keywords | Field | DocType |
bioelectric potentials,biological techniques,biomedical electrodes,biomembrane transport,microelectrodes,neurophysiology,HSPICE,action potentials,adhesion,circuit models,compartmental model,cultured neurons,equivalent electric-circuit approach,extracellular recording,general-purpose circuit simulation program,microelectrode arrays,neuro-electronic junction,neuron-microelectrode junction,neuronal membrane,sealing resistance | Experimental data,Neurophysiology,Computer science,Electronic engineering,Circuit models,Microelectrode | Journal |
Volume | Issue | ISSN |
51 | 5 | 0018-9294 |
Citations | PageRank | References |
20 | 2.92 | 4 |
Authors | ||
4 |
Name | Order | Citations | PageRank |
---|---|---|---|
S Martinoia | 1 | 158 | 20.68 |
Paolo Massobrio | 2 | 21 | 3.62 |
Marco Bove | 3 | 27 | 4.90 |
Giuseppe Massobrio | 4 | 20 | 3.26 |