Title
The Swiss-Prot Protein Knowledgebase And Its Supplement Trembl In 2003
Abstract
The SWISS-PROT protein knowledgebase (http: / / www. expasy. org/ sprot/ and http: / / www. ebi. ac. uk/ swissprot/) connects amino acid sequences with the current knowledge in the Life Sciences. Each protein entry provides an interdisciplinary overview of relevant information by bringing together experimental results, computed features and sometimes even contradictory conclusions. Detailed expertise that goes beyond the scope of SWISS-PROT is made available via direct links to specialised databases. SWISS-PROT provides annotated entries for all species, but concentrates on the annotation of entries from human ( the HPI project) and other model organisms to ensure the presence of high quality annotation for representative members of all protein families. Part of the annotation can be transferred to other family members, as is already done for microbes by the High-quality Automated and Manual Annotation of microbial Proteomes (HAMAP) project. Protein families and groups of proteins are regularly reviewed to keep up with current scientific findings. Complementarily, TrEMBL strives to comprise all protein sequences that are not yet represented in SWISS-PROT, by incorporating a perpetually increasing level of mostly automated annotation. Researchers are welcome to contribute their knowledge to the scientific community by submitting relevant findings to SWISS-PROT at swiss-prot@expasy.org.
Year
DOI
Venue
2003
10.1093/nar/gkg095
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
proteome,systems integration,proteins,proteomics,amino acid sequence,nucleic,protein sequence,protein family
Protein family,Annotation,Biology,UniProt,Manual annotation,Genetics,Archaeal Proteins
Journal
Volume
Issue
ISSN
31
1
0305-1048
Citations 
PageRank 
References 
674
120.52
21
Authors
12
Search Limit
100674
Name
Order
Citations
PageRank
Brigitte Boeckmann12256347.46
Amos Bairoch259811931.78
Rolf Apweiler367111644.94
Marie-Claude Blatter4758129.46
Anne Estreicher5724125.45
Elisabeth Gasteiger62571347.61
Maria Jesus Martin72793365.41
Karine Michoud8784144.70
Claire O'Donovan92584329.29
Isabelle Phan10898164.33
Sandrine Pilbout11710128.42
Michel Schneider12707129.22