Title
Enhancing phylogeography by improving geographical information from GenBank.
Abstract
Phylogeography is a field that focuses on the geographical lineages of species such as vertebrates or viruses. Here, geographical data, such as location of a species or viral host is as important as the sequence information extracted from the species. Together, this information can help illustrate the migration of the species over time within a geographical area, the impact of geography over the evolutionary history, or the expected population of the species within the area. Molecular sequence data from NCBI, specifically GenBank, provide an abundance of available sequence data for phylogeography. However, geographical data is inconsistently represented and sparse across GenBank entries. This can impede analysis and in situations where the geographical information is inferred, and potentially lead to erroneous results. In this paper, we describe the current state of geographical data in GenBank, and illustrate how automated processing techniques such as named entity recognition, can enhance the geographical data available for phylogeographic studies.
Year
DOI
Venue
2011
10.1016/j.jbi.2011.06.005
Journal of Biomedical Informatics
Keywords
Field
DocType
nucleic acid,geographical information,automated processing technique,geographical area,bioinformatics,molecular sequence data,sequence information,genbank entry,databases,geographical lineage,available sequence data,geographic locations,enhancing phylogeography,phylogeography,current state,geographical data,phylogeny
Phylogeography,Population,Information retrieval,Computer science,Data sequences,Bioinformatics,Phylogenetics,Named-entity recognition,Evolutionary biology,GenBank
Journal
Volume
Issue
ISSN
44 Suppl 1
S1
1532-0480
Citations 
PageRank 
References 
6
0.86
7
Authors
8
Name
Order
Citations
PageRank
Matthew Scotch112311.56
Indra Neil Sarkar223337.20
Changjiang Mei360.86
Robert Leaman491439.98
Kei-hoi Cheung566460.65
Pierina Ortiz681.22
Ashutosh Singraur760.86
Graciela Gonzalez862439.60