Title
PEAKS: identification of regulatory motifs by their position in DNA sequences.
Abstract
Many DNA functional motifs tend to accumulate or cluster at specific gene locations. These locations can be detected, in a group of gene sequences, as high frequency 'peaks' with respect to a reference position, such as the transcription start site (TSS). We have developed a web tool for the identification of regions containing significant motif peaks. We show, by using different yeast gene datasets, that peak regions are strongly enriched in experimentally-validated motifs and contain potentially important novel motifs.http://genomics.imim.es/peaks
Year
DOI
Venue
2007
10.1093/bioinformatics/btl568
Bioinformatics
Keywords
Field
DocType
supplementary data,peaks contact,different yeast gene datasets,experimentally-validated motif,gene sequence,regulatory motif,bioinformatics online,specific gene location,es supplementary information,high frequency,dna sequence,dna functional motif,transcription start site
Gene,Transcription (biology),Biology,Genomics,DNA,Yeast,DNA sequencing,Bioinformatics,Genetics
Journal
Volume
Issue
ISSN
23
2
1367-4811
Citations 
PageRank 
References 
3
0.49
5
Authors
3
Name
Order
Citations
PageRank
Nicolás Bellora130.49
Domènec Farré2443.59
M Mar Albà3726.46