Paper Info
Title
Assessment of brain interactivity in the motor cortex from the concept of functional connectivity and spectral analysis of fMRI data.
Abstract
Functional magnetic resonance imaging (fMRI) was used to assess the contributions of movement preparation and execution of a visuomotor task in a cerebral motor network. The functional connectivity of the voxel time series between brain regions in the frequency space was investigated by performing spectral analysis of fMRI time series. The regional interactivities between the two portions of the supplementary motor area (pre-SMA and SMA-proper) and the primary motor cortex (M1), defined as a seed region, were evaluated. The spectral parameter of coherence was used to describe a correlation structure in the frequency domain between two voxel-based time series and to infer the strength of the functional interaction within our presumed motor network of connections. The results showed meaningful differences of the functional interactions between the two portions of the SMA and the M1 area depending on the task conditions. This approach demonstrated the existence of a functional dissociation between the pre-SMA and SMA-proper subregions. We therefore conclude that spectral analysis is useful for identifying functional interactions of brain regions and might provide a powerful tool to quantify changes in connectivity profiles associated with various components of an experimental task.
Year
DOI
Venue
2008
10.1007/s00422-007-0198-5
Biological Cybernetics
Keywords
Field
DocType
Coherence,Functional Connectivity,Motor Area,Supplementary Motor Area,fMRI Data
Voxel,SMA*,Frequency domain,Neuroscience,Functional magnetic resonance imaging,Resting state fMRI,Supplementary motor area,Motor cortex,Primary motor cortex,Mathematics
Journal
Volume
Issue
ISSN
98
2
0340-1200
Citations 
PageRank 
References 
1
0.35
21
Authors
2
Name
Order
Citations
PageRank
S Fall110.35
G de Marco2283.29