Title
Integrative set enrichment testing for multiple omics platforms.
Abstract
Enrichment testing assesses the overall evidence of differential expression behavior of the elements within a defined set. When we have measured many molecular aspects, e.g. gene expression, metabolites, proteins, it is desirable to assess their differential tendencies jointly across platforms using an integrated set enrichment test. In this work we explore the properties of several methods for performing a combined enrichment test using gene expression and metabolomics as the motivating platforms.
Year
DOI
Venue
2011
10.1186/1471-2105-12-459
BMC Bioinformatics
Keywords
Field
DocType
Null Distribution, Joint Test, Enrichment Test, Logistic Regression Test, Competitive Test
Differential expression,Biology,Metabolomics,Genomics,Omics,Computational biology,Bioinformatics,Gene expression profiling,DNA microarray
Journal
Volume
Issue
ISSN
12
1
1471-2105
Citations 
PageRank 
References 
9
0.37
4
Authors
3
Name
Order
Citations
PageRank
Laila M. Poisson190.37
Jeremy M. G. Taylor2523.81
Debashis Ghosh349649.16