Title
The Universal Protein Resource (Uniprot): An Expanding Universe Of Protein Information
Abstract
The Universal Protein Resource (UniProt) provides a central resource on protein sequences and functional annotation with three database components, each addressing a key need in protein bioinformatics. The UniProt Knowledgebase (UniProtKB), comprising the manually annotated UniProtKB/Swiss-Prot section and the automatically annotated UniProtKB/TrEMBL section, is the preeminent storehouse of protein annotation. The extensive cross-references, functional and feature annotations and literature-based evidence attribution enable scientists to analyse proteins and query across databases. The UniProt Reference Clusters (UniRef) speed similarity searches via sequence space compression by merging sequences that are 100% (UniRef100), 90% (UniRef90) or 50% (UniRef50) identical. Finally, the UniProt Archive (UniParc) stores all publicly available protein sequences, containing the history of sequence data with links to the source databases. UniProt databases continue to grow in size and in availability of information. Recent and upcoming changes to database contents, formats, controlled vocabularies and services are described. New download availability includes all major releases of UniProtKB, sequence collections by taxonomic division and complete proteomes. A bibliography mapping service has been added, and an ID mapping service will be available soon. UniProt databases can be accessed online athttp://www.uniprot.org or downloaded at ftp://ftp.uniprot.org/pub/databases/.
Year
DOI
Venue
2006
10.1093/nar/gkj161
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Annotation,Sequence database,Information retrieval,Biology,UniProt,Universal Protein Resource,Controlled vocabulary,Data sequences,Protein Annotation,Bioinformatics,Genetics,Merge (version control)
Journal
34
Issue
ISSN
Citations 
Database-I
0305-1048
208
PageRank 
References 
Authors
27.78
16
16
Search Limit
100208
Name
Order
Citations
PageRank
Cathy H. Wu14169508.88
Rolf Apweiler267111644.94
Bairoch Amos320827.78
Natale Darren A420827.78
Barker Winona C520827.78
Boeckmann Brigitte620827.78
Ferro Serenella720827.78
Gasteiger Elisabeth820827.78
Hongzhan Huang92479346.17
Rodrigo Lopez104865744.83
Magrane Michele1124335.81
Maria Jesus Martin122793365.41
Mazumder Raja1320827.78
O'Donovan Claire1424335.81
N Redaschi152104283.38
Baris E Suzek16656111.13