Paper Info
Title
Analysis of the Proton Mediated Feedback Signals in the Outer Plexiform Layer of Goldfish Retina.
Abstract
Center-surround antagonistic receptive field in the retina is generated by negative feedback from horizontal cells (HCs) via a proton feedback mechanism [1]. In this study, the contribution of protons on the color opponent signal formation is analyzed. Increasing the buffer capacity of the external medium by 10 mM HEPES depolarized the dark membrane potential of HCs, and substantially increased hyperpolarizing responses to light stimulation. In contrast, feedback mediated depolarizing responses of H2 and H3 HCs were suppressed by HEPES. Moreover, depolarizing response onset of H2 and H3 HCs was significantly delayed compared to the hyperpolarizing responses. These indicate that proton plays an important role on the color opponent signal formation of HCs and that the feedback from H1 to H2 HCS is delayed by 10 - 20 ms. A similar delay might be applicable to other feedback pathways as well.
Year
DOI
Venue
2011
10.1007/978-3-642-24965-5_77
Lecture Notes in Computer Science
Keywords
Field
DocType
Retina,outer plexiform layer,horizontal cell,proton,feedback
Receptive field,Membrane potential,Proton,Pattern recognition,Biophysics,Retina,Computer science,Negative feedback,Outer plexiform layer,HEPES,Depolarization,Artificial intelligence
Conference
Volume
ISSN
Citations 
7064
0302-9743
0
PageRank 
References 
Authors
0.34
0
6
Name
Order
Citations
PageRank
Nilton Liuji Kamiji152.07
Masahiro Yamada200.34
Kazunori Yamamoto300.34
Hajime Hirasawa400.34
Makoto Kurokawa500.34
Shiro Usui6775198.35