Title
Image segmentation and bias correction via an improved level set method
Abstract
Intensity inhomogeneity causes considerable difficulty in the quantitative analysis of magnetic resonance (MR) images. Thus bias field estimation is a necessary pre-processing step before quantitative analysis of MR data. This paper presents a variational level set approach for bias correction and segmentation for images with intensity inhomogeneities. Our method is based on the observation that local intensity variations in relatively smaller regions are separable, despite the inseparability of the whole image. In the beginning we define a function for clustering the image pixels in a smaller neighborhood. The cluster centers in this objective function have a multiplicative factor that estimates the bias within the neighborhood. Generally the local intensity variations are described by the Gaussian distributions with different means and variances. In this work the objective functions are integrated over the entire domain with local Gaussian distribution of fitting energy, ultimately analyzing the data with a level set framework. Our method is able to capture bias of quite general profiles. Moreover, our model can also distinguish regions with similar intensity distribution with different variances. The proposed method has been rigorously validated with images acquired on variety of imaging modalities with promising results.
Year
DOI
Venue
2011
10.1016/j.neucom.2011.06.006
Neurocomputing
Keywords
Field
DocType
similar intensity distribution,objective function,bias correction,intensity inhomogeneity,local information,bias field estimation,quantitative analysis,improved level set method,bias field,local intensity variation,local gaussian distribution,intensity inhomogeneities,image segmentation,level set,gaussian distribution,magnetic resonance,level set method
Multiplicative function,Pattern recognition,Level set method,Segmentation,Level set,Image segmentation,Gaussian,Pixel,Artificial intelligence,Cluster analysis,Mathematics
Journal
Volume
Issue
ISSN
74
17
Neurocomputing
Citations 
PageRank 
References 
18
0.72
29
Authors
4
Name
Order
Citations
PageRank
Yunjie Chen1362.14
Jianwei Zhang235371.98
Arabinda Mishra31644.72
Jianwei Yang45812.73