Title
A modular database architecture enabled to comparative sequence analysis
Abstract
The beginning of post-genomic era is characterized by a rising numbers of public collected genomes. The evolutionary relationship among these genomes may be caught by means of the comparative analysis of sequences, in order to identify both homologous and noncoding functional elements. In this paper we report on the on-going BIOBITS project. It is focused on studies concerning the bacterial endosymbionts, since they offer an excellent model to investigate important biological events, such as organelle evolution, genome reduction, and transfer of genetic information among host lineages. The BIOBITS goal is two-side: on the one hand, it pursues a logical data representation of genomic and proteomic components. On the other hand, it aims at the development of software modules allowing the user to retrieve and analyze data in a flexible way.
Year
DOI
Venue
2011
10.1007/978-3-642-23740-9_6
T. Large-Scale Data- and Knowledge-Centered Systems
Keywords
Field
DocType
logical data representation,genetic information,biobits goal,functional element,excellent model,bacterial endosymbionts,comparative sequence analysis,genome reduction,on-going biobits project,modular database architecture,comparative analysis,evolutionary relationship,database architecture,data warehouse,case based reasoning
Data warehouse,Genome,Data architecture,Data mining,Software modules,Biology,Logical data model,Modular design,Case-based reasoning,Sequence analysis
Journal
Volume
ISSN
Citations 
4
0302-9743
0
PageRank 
References 
Authors
0.34
18
10
Name
Order
Citations
PageRank
Paola Bonfante100.34
Francesca Cordero26313.42
Stefano Ghignone301.35
Dino Ienco429542.01
Luisa Lanfranco501.35
Giorgio Leonardi617920.36
Rosa Meo7603113.80
Stefania Montani890181.42
Luca Roversi918321.03
Alessia Visconti1082.85