Title
Investigating the Detection of Adverse Drug Events in a UK General Practice Electronic Health-Care Database.
Abstract
Data-mining techniques have frequently been developed for Spontaneous reporting databases. These techniques aim to find adverse drug events accurately and efficiently. Spontaneous reporting databases are prone to missing information, under reporting and incorrect entries. This often results in a detection lag or prevents the detection of some adverse drug events. These limitations do not occur in electronic health-care databases. In this paper, existing methods developed for spontaneous reporting databases are implemented on both a spontaneous reporting database and a general practice electronic health-care database and compared. The results suggests that the application of existing methods to the general practice database may help find signals that have gone undetected when using the spontaneous reporting system database. In addition the general practice database provides far more supplementary information, that if incorporated in analysis could provide a wealth of information for identifying adverse events more accurately.
Year
DOI
Venue
2013
10.2139/SSRN.2829246
CoRR
Keywords
Field
DocType
health care
Health care,Data science,Under-reporting,Adverse effect,General practice,Database,Mathematics
Journal
Volume
Citations 
PageRank 
abs/1307.1078
1
0.37
References 
Authors
0
6
Name
Order
Citations
PageRank
Jenna Marie Reps1324.40
Jan Feyereisl213110.20
J. M. Garibaldi31425146.38
Uwe Aickelin41679153.63
Jack E. Gibson5212.91
Richard B. Hubbard6253.28