Name
Title | ||
|---|---|---|
Predbalb/C: A System For The Prediction Of Peptide Binding To H2(D) Molecules, A Haplotype Of The Balb/C Mouse |
Abstract | ||
|---|---|---|
PREDBALB/c is a computational system that predicts peptides binding to the major histocompatibility complex-2 (H2(d)) of the BALB/c mouse, an important laboratory model organism. The predictions include the complete set of H2(d) class I ( H2-K-d, H2-L-d and H2-D-d) and class II (I-E-d and I-A(d)) molecules. The prediction system utilizes quantitative matrices, which were rigorously validated using experimentally determined binders and non-binders and also by in vivo studies using viral proteins. The prediction performance of PREDBALB/c is of very high accuracy. To our knowledge, this is the first online server for the prediction of peptides binding to a complete set of major histocompatibility complex molecules in a model organism (H2(d) haplotype). PREDBALB/c is available at http://antigen.i2r.a-star.edu.sg/predBalbc/. |
Year | DOI | Venue |
|---|---|---|
2005 | 10.1093/nar/gki479 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
internet,database,ligands,computational biology,affinity,haplotypes,epitopes,mhc class i,immune response | Epitope,Biology,Antigen,Peptide,MHC class I,BALB/c Mouse,Major histocompatibility complex,Model organism,Histocompatibility,Molecular biology | Journal |
Volume | Issue | ISSN |
33 | Web-Server-Issue | 0305-1048 |
Citations | PageRank | References |
5 | 0.90 | 4 |
Authors | ||
5 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| G.L. Zhang | 1 | 208 | 16.91 |
| Kellathur N. Srinivasan | 2 | 97 | 5.49 |
| Anitha Veeramani | 3 | 71 | 5.69 |
| J. Thomas August | 4 | 143 | 7.36 |
| Vladimir Brusic | 5 | 551 | 63.37 |