Name
Abstract | ||
|---|---|---|
Diffusion tensor MRI (DTI) is now a widely used modality to investigate the fiber tissues in vivo, especially the white matter in brain. An automatic pipeline is described in this paper to conduct a localized voxel-wise multiple-subject group comparison study of DTI. The pipeline consists of 3 steps: 1) Preprocessing, including image format converting, image quality check, eddy-current and motion artifact correction, skull stripping and tensor image estimation, 2) study-specific unbiased DTI atlas computation via affine followed by fluid nonlinear registration and warping of all individual DTI images into the common atlas space to achieve voxel-wise correspondence, 3) voxelwise statistical analysis via heterogeneous linear regression and wild bootstrap technique for correcting for multiple comparisons. This pipeline was applied to process data from a fitness and aging study and preliminary results are presented. The results show that this fully automatic pipeline is suitable for voxel-wise group DTI analysis. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.1109/ISBI.2009.5193172 | ISBI |
Keywords | Field | DocType |
voxel-wise statistical analysis,voxel-wise analysis,image format,individual dti image,localized voxel-wise multiple-subject group,voxel-wise group analysis,image quality check,group comparison,mri,study-specific unbiased dti atlas,automatic pipeline,voxel-wise correspondence,tensor image estimation,diffusion tensor,voxel-wise group dti analysis,image registration,correlation,diffusion tensor imaging,regression analysis,multiple comparisons,tensile stress,image quality,bioinformatics,statistical analysis,testing,biomedical imaging,pipelines,image formation,linear regression,eddy current,biomedical research | Affine transformation,Voxel,Computer vision,Diffusion MRI,Image warping,Pattern recognition,Medical imaging,Computer science,Image quality,Preprocessor,Artificial intelligence,Image registration | Conference |
ISSN | Citations | PageRank |
1945-7928 | 4 | 0.44 |
References | Authors | |
6 | 7 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Zhexing Liu | 1 | 69 | 4.18 |
| Hongtu Zhu | 2 | 252 | 30.21 |
| Bonita L Marks | 3 | 4 | 0.44 |
| Laurence M Katz | 4 | 4 | 0.44 |
| Casey B Goodlett | 5 | 4 | 0.44 |
| Guido Gerig | 6 | 4795 | 540.21 |
| Martin Styner | 7 | 1349 | 116.30 |