Title
How geometration reduces the velocity of DNA in gel electrophoresis
Abstract
New correction is derived to the velocity of geometrating molecules in gel. The formalism takes into account the random character of the gel medium. The correction comes from the possibility of two simultaneous hookings of a molecule at gel fibres. The calculated velocity is shown to be inversely proportional to 1+3ξ/4+ξ 2 /3, where ξ= s/b, s is the molecule length and b is a mean free path. This result shows that the velocity of DNA decreases with the molecule length sharper, than it was previously estimated.
Year
DOI
Venue
2002
10.1078/1431-7613-00057
Theory in Biosciences
Keywords
Field
DocType
mobility,free path,random medium
Mean free path,Molecular physics,Biology,Molecule,Gel electrophoresis,DNA,Genetics,Random media,Molecular biology
Journal
Volume
Issue
ISSN
121
2
Theory in Biosciences
Citations 
PageRank 
References 
0
0.34
0
Authors
2
Name
Order
Citations
PageRank
M. J. Krawczyk122.79
Krzysztof Kułakowski23713.14