Title
Stability of the linearization method in compartmental analysis
Abstract
Purpose - The purpose of this paper is to prove that under sufficient conditions the linearization method used for identifying a nonlinear bicompartmental system is stable. Design/methodology/approach - The problem of identifying a nonlinear compartmental system appears as badly stated a priori. In fact the problem is not to identify the general behavior law of exchange between compartments, but to assume these laws known such as in Michaelis-Menten systems or in polynomial compartmental systems with coefficients that need to be identified. It has been proved previously that with a linearization method an approximation call be obtained to the identification of these nonlinear systems. To Validate this method, a stability study is necessary. Findings - Sufficient conditions are established for the evolution law of a nonlinear bicompartmental system under which the linearization method is stable, and an upper bound is given on the approximation error - with an application, in the last section to the case of an open Michaelis-Menten system. Originality/value - The paper is of value in establishing sufficient conditions about the evolution law of a nonlinear System in order to show that this method is stable and to give an upper bound on the approximation error.
Year
DOI
Venue
2009
10.1108/03684920910962641
KYBERNETES
Keywords
Field
DocType
Cybernetics,Numerical analysis,Modelling,Linear structure equation modelling
Mathematical optimization,Nonlinear system,Polynomial,Control theory,Upper and lower bounds,A priori and a posteriori,Feedback linearization,Numerical analysis,Approximation error,Linearization,Mathematics
Journal
Volume
Issue
ISSN
38
5
0368-492X
Citations 
PageRank 
References 
0
0.34
0
Authors
3
Name
Order
Citations
PageRank
Belkhaled Hebri100.34
Salim Khelifa200.68
Y. Cherruault3206.08